Bim (Phospho Thr56/116) Rabbit pAb
簡要描述：Bim (Phospho Thr56/116) Rabbit pAb宿主: Rabbit,polyclonal反應性: Human, Mouse,Rat應用: IHC,WB
產(chǎn)品型號： YP-Ab-17144
所屬分類：多克隆抗體
更新時間：2024-10-31
詳細說明：
Bim (Phospho Thr56/116) Rabbit pAb
抗體，也叫免疫球蛋白（Ig），是一種能特異性結合抗原的糖蛋白，而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質。在體內(nèi)，抗體是由于外源性分子的侵襲而產(chǎn)生的。抗體以一個或者多個Y字形單體存在，每個Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據(jù)它們的分子量大小來命名的。Y字形結構的頂端是可變區(qū)，為抗原結合部位。任何一個抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結構上的差異），每一個抗體的重鏈則決定了它的類或型。
保存溫度：-20℃
產(chǎn)品詳情
This antibody detects endogenous levels of Bim (Phospho Thr56/116) Rabbit pAb at Human, Mouse,Rat
免疫原詳細信息
Synthesized peptide derived from human Bim (Phospho Thr56/116)
相關試劑
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
背景
BCL2 like 11(BCL2L11) Homo sapiens The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]。
天津俊達生物科技有限公司，是從事實驗室耗材銷售的現(xiàn)代化生物科技企業(yè)，公司本著“誠信為本，互利共贏"的核心價值觀，秉承“以市場為導向，提供服務"的宗旨為各大院校、科研單位、第三方實驗室檢測機構等提供的產(chǎn)品和服務。目前公司主要經(jīng)營分子生物學、細胞生物學、免疫學等生物學產(chǎn)品，多種實驗室耗材 歡迎垂詢！
備注：圖片僅供參考。僅供科研，不可用于臨床。
